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Consider the following four statements (i-iv) regarding kidney transplant and select the two correct ones out of these. (i) Even if a kidney transplant is proper the recipient may need to take immune suppressants for a long time (ii) The cell mediated immune response is responsible for the graft rejection (iii) The B lymphocytes are responsible for rejection of the graft (iv) The acceptance or rejection of a kidney transplant depends on specific interferons The two correct statements are:

1. (i) and (iii)
2. (ii) and (iv)
3. (i) and (ii)
4. (i) and (iv)

Correct answer: (i) and (ii)

Solution

A transplanted kidney can still be rejected because the recipient’s immune system recognizes it as foreign, so immunosuppressants are often needed long term. Graft rejection is mainly mediated by cell-mediated immunity, especially T lymphocytes, not by B cells or interferons.

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