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Which of the following causes an increase in sodium reabsorption in the distal convoluted tubule?

1. Increase in aldosterone levels
2. Increase in antidiuretic hormone levels
3. Decrease in aldosterone levels
4. Decrease in antidiuretic hormone levels

Correct answer: Increase in aldosterone levels

Solution

Aldosterone acts on the distal convoluted tubule and collecting duct to increase sodium reabsorption by upregulating sodium channels and the Na+/K+ ATPase. ADH mainly increases water reabsorption, not sodium reabsorption.

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