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Which of the following pair is characterised by swollen lips, thick pigmented skin of hands and legs and irritability?

1. Thiamine — Beri-Beri
2. Protein — Kwashiorkor
3. Nicotinamide — Pellagra
4. Iodine — Goitre

Correct answer: Nicotinamide — Pellagra

Solution

Nicotinamide (niacin, vitamin B3) deficiency causes pellagra, classically marked by dermatitis, diarrhea, and dementia/irritability. The skin changes can include thickened, pigmented areas and swollen lips.

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