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Angiotensinogen is a protein produced and secreted by:

1. endothelial cells (lining the blood vessels)
2. liver cells
3. juxtaglomerular (JG) cells
4. macula densa cells

Correct answer: liver cells

Solution

Angiotensinogen is synthesized and released into the bloodstream by the liver. The kidney’s JG cells release renin, which acts on angiotensinogen, while macula densa cells sense sodium and flow.

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