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Crossing over takes place between which chromatids and in which stage of the cell cycle?

1. Non-sister chromatids of non-homologous chromosomes at Pachytene stage of prophase I.
2. Non-sister chromatids of non-homologous chromosomes at Zygotene stage of prophase I.
3. Non-sister chromatids of homologous chromosomes at Pachytene stage of prophase I.
4. Non-sister chromatids of homologous chromosomes at Zygotene stage of prophase I.

Correct answer: Non-sister chromatids of homologous chromosomes at Pachytene stage of prophase I.

Solution

Crossing over occurs between non-sister chromatids of homologous chromosomes, not non-homologous ones. It takes place in pachytene of prophase I, after synapsis has occurred in zygotene.

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