Exams › NEET › Biology

Colchicine is employed to diploidize a haploid cell as it

1. inhibits mitosis
2. inhibits formation of mitotic spindle
3. allows replication of DNA twice in one cell cycle
4. inhibits formation of centromere

Correct answer: inhibits formation of mitotic spindle

Solution

Colchicine binds tubulin and prevents microtubule polymerization, so the mitotic spindle cannot form. Without spindle formation, chromosomes fail to segregate, allowing chromosome doubling and diploidization of a haploid cell.

Related NEET Biology questions

• Cell division can not be stopped in phase of the cell cycle.
• Some dividing cells exit the cell cycle and enter vegetative inactive stage. This is called quiescent stage (G₀). This process occurs at the end of
• Identify the correct statement with regard to G₁ phase (Gap 1) of interphase.
• In ‘S’ phase of the cell cycle:
• During which phase(s) of cell cycle, amount of DNA in a cell remains at 4C level if the initial amount is denoted as 2C?
• A somatic cell that has just completed the S phase of its cell cycle, as compared to gamete of the same species, has:

⚔️ Practice NEET Biology free + battle 1v1 →