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During the metaphase stage of mitosis spindle fibres attach to chromosomes at

1. Centromere
2. Kinetochore
3. Both centromere and kinetochore
4. Centromere, kinetochore and areas adjoining centromere

Correct answer: Kinetochore

Solution

Spindle fibres attach to the kinetochore, a protein complex assembled on the centromere of each chromosome. The centromere is the region, while the kinetochore is the actual binding site for microtubules.

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