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The correct sequence of events occur during mitosis would be as follows: (i) DNA condensation occurs so that chromosomes become visible during early to mid-prophase. (ii) Disassembly of nuclear membrane begins at late prophase or transition to metaphase. (iii) Chromosomes align at equator during metaphase. (iv) Centromere division occurs during anaphase forming daughter chromosomes. (v) During anaphase segregation also occurs in which daughter chromosomes separate and move to opposite poles. (vi) Telophase finally leads to formation of two daughter nuclei.

1. (a) The correct sequence of events occur during mitosis would be as follows: (i) DNA condensation occurs so that chromosomes become visible during early to mid-prophase. (ii) Disassembly of nuclear membrane begins at late prophase or transition to metaphase. (iii) Chromosomes align at equator during metaphase. (iv) Centromere division occurs during anaphase forming daughter chromosomes. (v) During anaphase segregation also occurs in which daughter chromosomes separate and move to opposite poles. (vi) Telophase finally leads to formation of two daughter nuclei.
2. (b) During anaphase Anaphase Promoting Complex (APC) is a protein necessary for separation of daughter chromosomes. A defective APC will cause the chromosomes fail to segregate during anaphase.
3. (c) Attachment of microtubules to chromosomes is mediated by kinetochores, which actively monitor spindle formation and prevent premature anaphase onset during mitosis.
4. (d) Synapsis is the pairing of two homologous chromosomes that occurs during meiosis. It allows matching-up of homologous pairs prior to their segregation, and possible chromosomal crossover between them. Synapsis takes place during prophase I, of zygotene of meiosis.

Correct answer: (a) The correct sequence of events occur during mitosis would be as follows: (i) DNA condensation occurs so that chromosomes become visible during early to mid-prophase. (ii) Disassembly of nuclear membrane begins at late prophase or transition to metaphase. (iii) Chromosomes align at equator during metaphase. (iv) Centromere division occurs during anaphase forming daughter chromosomes. (v) During anaphase segregation also occurs in which daughter chromosomes separate and move to opposite poles. (vi) Telophase finally leads to formation of two daughter nuclei.

Solution

The correct sequence of events during mitosis is provided in option (a).

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