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consider the following statements each with one or two blanks. (i) The ascending limb of loop of Henle is impermeable to (1) but allows transport of (2) (ii) (3) and (4) play a significant role in producing a concentrated urine. (iii) A fall in glomerular blood flow/glomerular blood pressure/GFR can activate the JG cells to release (5) Which one of the following options correctly fills the blanks in any two of the statements?

1. (1)-water, (2)-electrolytes, (5)-renin
2. (3)-Henle's loop, (4)-vasa recta, (5)-angiotensin
3. (1)-electrolytes, (2)-water, \( (3)- \) РСТ, \( (4)- \) DCT
4. (3)-Henle's loop, (4)-vasa recta, (5)-angiotensinogen

Correct answer: (1)-water, (2)-electrolytes, (5)-renin

Solution

The ascending limb of Henle’s loop is impermeable to water but actively transports electrolytes, so (1) = water and (2) = electrolytes. Also, a fall in renal perfusion/GFR stimulates juxtaglomerular cells to release renin, not angiotensin or angiotensinogen.

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