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The absolute configuration of CO2H | H—C—OH | H—C—Cl | CH3 is:

1. (2R, 3S)
2. (2S, 3R)
3. (2S, 3S)
4. (2R, 3R)

Correct answer: (2S, 3R)

Solution

The correct option (2S, 3R) is determined by analyzing the chiral centers at carbon 2 and carbon 3. At carbon 2, the highest priority group is the carboxylic acid (CO2H), which gives it an 'S' configuration, while at carbon 3, the chlorine (Cl) takes priority over the hydroxyl (OH) and methyl (CH3) groups, resulting in an 'R' configuration.

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