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In osazone formation, which structural unit must be present for the reaction to occur effectively?

1. –CH2OCH3
2. –CH2OH
3. –CHOCH3
4. –CHO

Correct answer: –CHO

Solution

Osazone formation with phenylhydrazine requires a carbonyl adjacent to a CHOH, i.e. an alpha-hydroxy aldehyde/ketone. Of the choices the -CHO group is the structural unit that allows osazone formation.

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