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Which chemical stimulates the secretion of pepsin (and HCl) in the stomach?

1. Anti histamine
2. Cimetidine
3. Histamine
4. Zantac

Correct answer: Histamine

Solution

Histamine stimulates the stomach to secrete HCl and pepsin; cimetidine, ranitidine (Zantac) and antihistamines act against histamine to reduce secretion.

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