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How many asymmetric (chiral) carbon atoms are present in alpha-D-(+)-glucose?

1. 2
2. 3
3. 4
4. 5

Correct answer: 4

Solution

In alpha-D-(+)-glucose (open chain), C1 is the aldehyde carbon and C6 is CH2OH — neither is chiral. Carbons C2, C3, C4, and C5 each bear four different substituents, making them chiral. So there are 4 asymmetric carbons.

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