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ExamsJEE AdvancedChemistry

Among the various structural forms in which glucose can exist, which isomer is the most stable?

  1. Open-chain aldehydic form
  2. Cyclic alpha-pyranose form
  3. Open-chain keto form
  4. Cyclic beta-pyranose form

Correct answer: Cyclic alpha-pyranose form

Solution

Glucose strongly prefers the cyclic pyranose hemiacetal forms over the open-chain aldehydic or keto forms due to ring stabilisation. Of the four options provided, the cyclic alpha-pyranose form is far more stable than either open-chain form listed, making it the best answer here.

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