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Correct answer: f(0)f(4) < 0
Write f(x)=a(x-1)(x-2)(x-3) with a nonzero. Then f(0)=a(-1)(-2)(-3)=-6a and f(4)=a(3)(2)(1)=6a, so f(0)f(4)=-36a^2, which is strictly negative for every nonzero a. Hence the statement that must be true is f(0)f(4)<0 (index 0), not f(0)f(4)>0.
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